serial	Pathway	Set Size	Percent Up	NTk Stat	NTk q-value	NTk Rank	NEk Stat	NEk q-value	NEk Rank
1	Signaling by Interleukins	83	68.7	-4.63	0	6	-2.33	1	7
2	Chemokine receptors bind chemokines	30	93.3	-6.25	0	1	-2.17	1	12.5
3	Interleukin-1 processing	7	85.7	-4.03	0	17	-3.09	0.814	1.5
4	Interferon alpha/beta signaling	41	80.5	-5.18	0	3	-2.01	1	21
5	Toll Receptor Cascades	90	71.1	-4.5	0	8	-2.03	1	20
6	Costimulation by the CD28 family	39	69.2	-4.05	0	16	-2.07	1	16.5
7	Regulation of pyruvate dehydrogenase (PDH) complex	10	10	3.23	0	34	3.09	0.814	1.5
8	PD-1 signaling	13	84.6	-4.46	0	10	-1.96	1	27
9	TRAF6 mediated NF-kB activation	20	75	-3.28	0	33	-2.37	1	6
10	Interferon Signaling	99	65.7	-4.34	0	12	-1.91	1	30.5
11	Interleukin-3, 5 and GM-CSF signaling	35	77.1	-3.51	0	32	-2.2	1	11
12	Antigen Activates B Cell Receptor Leading to Generation of Second Messengers	21	95.2	-3.68	0	29	-2.12	1	15
13	Phosphorylation of CD3 and TCR zeta chains	11	90.9	-4.46	0	9	-1.87	1	35.5
14	Death Receptor  Signalling	10	90	-3.22	0	35	-2.23	1	10
15	Extrinsic Pathway for Apoptosis	10	90	-3.22	0	35	-2.23	1	10
16	Activated TLR4 signalling	76	69.7	-3.98	0	20	-1.94	1	28
17	Trafficking and processing of endosomal TLR	6	100	-3.09	0.0233	39	-2.17	1	12.5
18	Cytosolic sensors of pathogen-associated DNA	21	76.2	-3.09	0.0233	39	-2.05	1	18.5
19	Toll Like Receptor 4 (TLR4) Cascade	80	68.8	-3.71	0	28	-1.88	1	33
20	RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways	47	63.8	-3.09	0.0233	39	-2	1	22.5
21	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	33	84.8	-4.78	0	4	-1.7	1	59
22	Apoptosis	101	69.3	-2.88	0.0377	48	-2.05	1	18.5
23	Regulation of Insulin Secretion by Fatty Acids Bound to GPR40 (FFAR1)	7	100	-2.65	0.0618	63	-2.58	1	4
24	Regulation of Insulin Secretion by Free Fatty Acids	7	100	-2.65	0.0618	63	-2.58	1	4
25	RIP-mediated NFkB activation via DAI	18	77.8	-2.65	0.0618	63	-2.29	1	8.5
26	MyD88:Mal cascade initiated on plasma membrane	69	68.1	-3.09	0.0233	39	-1.87	1	35.5
27	Toll Like Receptor 2 (TLR2) Cascade	69	68.1	-3.09	0.0233	39	-1.87	1	35.5
28	Toll Like Receptor TLR1:TLR2 Cascade	69	68.1	-3.09	0.0233	39	-1.87	1	35.5
29	Toll Like Receptor TLR6:TLR2 Cascade	69	68.1	-3.09	0.0233	39	-1.87	1	35.5
30	Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon	9	77.8	-2.65	0.0618	63	-2.14	1	14
31	Translocation of ZAP-70 to Immunological synapse	9	88.9	-3.72	0	27	-1.74	1	53.5
32	DAI mediated induction of type I IFNs	20	75	-2.75	0.0532	55.5	-1.98	1	25
33	MyD88-independent cascade	65	67.7	-3.09	0.0233	39	-1.8	1	45
34	Toll Like Receptor 3 (TLR3) Cascade	65	67.7	-3.09	0.0233	39	-1.8	1	45
35	TCR signaling	42	57.1	-2.88	0.0377	48	-1.84	1	39.5
36	Toll Like Receptor 9 (TLR9) Cascade	68	66.2	-2.88	0.0377	48	-1.84	1	39.5
37	TRAF3-dependent IRF activation pathway	11	72.7	-2.75	0.0532	55.5	-1.88	1	33
38	Generation of second messenger molecules	20	65	-2.88	0.0377	48	-1.79	1	47.5
39	Interleukin-6 signaling	7	85.7	-2.37	0.109	82	-2.07	1	16.5
40	NFkB and MAP kinases activation mediated by TLR4 signaling repertoire	60	66.7	-2.75	0.0532	55.5	-1.76	1	50.5
41	TRAIL  signaling	5	80	-2.29	0.12	93	-2	1	22.5
42	Interleukin-2 signaling	34	73.5	-2.51	0.082	73	-1.81	1	43
43	Signal regulatory protein (SIRP) family interactions	8	87.5	-2.29	0.12	93	-1.98	1	25
44	Activation of BH3-only proteins	9	77.8	-2.07	0.167	113	-2.41	1	5
45	Interleukin-7 signaling	8	87.5	-2.05	0.17	116	-2.65	1	3
46	Interleukin receptor SHC signaling	21	81	-2.51	0.082	73	-1.79	1	47.5
47	Activation of Matrix Metalloproteinases	18	77.8	-2.58	0.0716	69	-1.74	1	53.5
48	Degradation of the extracellular matrix	18	77.8	-2.58	0.0716	69	-1.74	1	53.5
49	Intrinsic Pathway for Apoptosis	20	75	-2.05	0.17	116	-2.29	1	8.5
50	Negative regulators of RIG-I/MDA5 signaling	20	65	-2.46	0.0946	75	-1.76	1	50.5